Genevac evaporators are designed to be as flexible as possible. Available options and accessories include an extensive range of sample holders, designed to provide maximum protection of samples and faster drying times, and sample handling tools such as SampleGenie™ that improve laboratory workflow. Options such as HCl resistance and Inert Gas Purge are available to protect operators, samples and systems.
Sample Holders
evaporators are designed to combine rapid and safe evaporation with high capacity and a wide variety of sample formats. In order to optimise the evaporation performance achieved it is important to select the correct sample holder for your particular application. Genevac samples holders are manufactured from solid aluminium to very precise specifications and are mass balanced to ensure smooth running of the evaporator.
Genevac HT & EZ2 Accessories and Spares Brochure
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SampleGenie
Drying Large Volumes Directly into Vials
SampleGenie technology, in conjunction with Genevac Rocket Synergy, HT and EZ-2 series evaporators, enables large sample volumes to be dried directly into vials, eliminating a number of time-consuming sample handling steps and the attendant risk of errors.
- Reduce processing and evaporation times by up to 66%.
- SampleGenie compatible with a wide range of HPLC, GC and storage vial sizes.
- Proven methodology for environmental analysis, metabolism & toxicology studies, food & beverage research and post purification protocols in life science research.
Traditionally protocols for concentration of chromatographic fractions have involved drying multiple fractions in an evaporator, re-suspending pooled fractions into a single vial and then re-drying before storage and analysis. Even with modern centrifugal evaporators such processes typically take 2-3 days to complete. Now fractions can be pooled into a SampleGenie flask and dried directly into a submission vial in one evaporation run.
Concentration for Analysis flier
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JetRotors
miVac are the only vacuum concentrators of their class to be supplied with rotors made from solid aluminium. The JetRotors range provides very high performance concentration compared to rotors made from plastic, or of an open construction. Speed increases compared with polypropylene types range between 40% and 200%, depending on sample format.
- Solid aluminium rotors
- Faster concentration
- Wide range of compatible labware
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HCI Resistance
Genevac evaporators are robust systems designed to be resistant to the most common solvents and acids used within the chemistry laboratory, including TFA, DCM (methylene chloride), and DMSO.
For laboratories who wish to use strong acid chlorides, special models of Genevac systems exist which are specifically designed to be resistant to these highly corrosive acids. Some manufacturers claim that their unmodified systems are resistant to HCl, however the experience of Genevac engineers shows that to be truly suitable for routine evaporation of acid chlorides special resistant materials such as Hastelloy® and PTFE must be used in place of materials which would suffer from HCl attack. Materials such as these are used in Genevac HCl resistant systems.Inert Gas Purge
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Carbon disulfide
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Diethyl ether
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1,2-dimethoxyethane
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2-ethoxyethanol
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Hydrogen cyanide
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Pentane
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Triethylsilane
Exalt Controlled Crystallisation
Exalt is a new technology developed by Genevac with partners in the field of pharmaceutical small molecule crystallisation. Exalt enables a wide range of solvents to be evaporated at the same time, and all at the same slow rate and is used for polymorph screening and stable form identification. Therefore, DCM and Toluene can be placed in the same system and evaporated such that both samples dry at the same time. Exalt may be used for up to 3ml of solvent within the boiling point of 40ºC to 165ºC – DCM to DMAc. The evaporation time can be controlled to range from 6 hours to 72 hours, or more, as required for most solvents in this boiling point range. The system can deliver polymorphs of a drug at the same time, in a controlled and reproducible way
Crystals of Ibuprofen produced by Exalt from ethanol (L) and ethyl acetate (R).
Exalt uses a special holder for vials which allows a selection of baffles to be placed on top of the vial to slow the evaporation rate of
the volatile solvents. Size and number of baffles are selected to be most restrictive for the most volatile solvents, and least restrictive to the less volatile solvents. In some cases no baffle is required. The holder is then placed in a Genevac HT series evaporator which cycles the samples at atmosphere and at a slightly reduced pressure for the duration of the process.
Exalt is being used and/or evaluated by several major Pharmaceutical companies throughout the world.
Documents and Downloads
Novartis Pharmaceuticals feedback on their work with Exalt technology is in this presentation. The presentation is probably best read in conjunction with this review paper which adds detail. For more information, please contact us or download the Exalt brochure sheet.
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Infinity Trolley
Infinity is a modular trolley, designed to accommodate a range of Genevac evaporation equipment in a number of configurations to suit customer requirements. It minimizes the footprint of the supported system, freeing valuable bench or fume hood space and allows the system to be moved easily for service access. 
Infinity Trolley Brochure.PDF
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