{"id":539,"date":"2014-12-30T09:30:28","date_gmt":"2014-12-30T09:30:28","guid":{"rendered":"http:\/\/iss-lab.com\/wordpress\/?page_id=539"},"modified":"2024-04-25T15:42:11","modified_gmt":"2024-04-25T11:42:11","slug":"lyostar-3","status":"publish","type":"page","link":"https:\/\/iss-lab.com\/index.php\/products-technologies\/freeze-dryers\/floor-model-traypilot-lyophilizers\/lyostar-3\/","title":{"rendered":"Hull LyoStar 4.0 R&amp;D\/Process Development Freeze Dryer"},"content":{"rendered":"<p><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/SP-Hull-LyoStar-4.0-Spec-Sheet.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-3069 size-full alignright\" src=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/SP-HULL-LYOSTAR-4_modified.png\" alt=\"\" width=\"339\" height=\"589\" srcset=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/SP-HULL-LYOSTAR-4_modified.png 339w, https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/SP-HULL-LYOSTAR-4_modified-173x300.png 173w\" sizes=\"(max-width: 339px) 100vw, 339px\" \/><\/a><\/p>\n<p>Ideal for rapid lyophilization cycle development, optimization and scale-up, the Hull LyoStar\u00ae 4.0 R&amp;D and Process Development Freeze Dryer incorporates the very latest innovations in freeze-drying technology. Ensure precise process control and reliability, and protect your valuable product, with us!<\/p>\n<ul>\n<li>Unparalleled uniformity \u2013 superior shelf temperature mapping and rapid shelf freezing<\/li>\n<li>Ecologically sound \u2013 reduced carbon footprint with eco-friendlier refrigerant gas<\/li>\n<\/ul>\n<p>The Hull LyoStar 4.0 R&amp;D and Process Development Freeze Dryer is designed and built to speed your biologic to market, with significant advancements in freeze dryer engineering. Based on a full-scale production freeze dryer to support rapid-scale-up, the Hull LyoStar 4.0 is a pilot-scale lyophilizer offering superior shelf mapping and rapid shelf freezing for unmatched process accuracy and reliability.<\/p>\n<p>Including a cutting-edge suite of Process Analytical Technology (PAT) tools, SP\u2019s Line of Sight\u2122 suite of technologies helps you overcome critical lyophilization challenges during development, scale up and manufacture of a biologic.<\/p>\n<p>These technologies include:<\/p>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/products\/lyoflux-200-tdlas-sensors\/\" target=\"_blank\" rel=\"noopener\">LyoFlux\u00ae TDLAS<\/a>\u00a0Sensors for vapor mass flow measurement<\/li>\n<li><a href=\"https:\/\/scientificproducts.com\/products\/smart-freeze-dryer-technology\/\" target=\"_blank\" rel=\"noopener\">AutoMTM\/SMART\u2122<\/a>\u00a0Freeze Dryer Technology, a primary drying cycle optimization tool<\/li>\n<li><a href=\"https:\/\/scientificproducts.com\/products\/controlyo-nucleation-technology\/\" target=\"_blank\" rel=\"noopener\">ControLyo\u00ae<\/a>\u00a0Nucleation Technology giving pinpoint control of freezing point<\/li>\n<li><a href=\"https:\/\/scientificproducts.com\/products\/tempris-wireless-sensors\/\" target=\"_blank\" rel=\"noopener\">Tempris \u00ae\u00a0<\/a>Wireless Sensors for real-time product temperature measurement<\/li>\n<\/ul>\n<h4 class=\"wp-block-heading has-text-color has-medium-font-size\">Features &amp; Benefits<\/h4>\n<ul>\n<li>Get to market faster \u2013 sophisticated instrumentation set, advanced cycle development and optimization features decrease cycle development time and conserve valuable API<\/li>\n<li>You can never be too informed \u2013 LyoStar 4.0 provides more product and process information such as dried layer resistance, heat flow, mass transfer, and how different freezing protocols impact cake resistance<\/li>\n<li>Easily scalable \u2013 advanced, reliable, and scalable lyophilization technologies, along with Process Analytical Technology (PAT) tools, support smooth scale-up from process development through to manufacturing<\/li>\n<li>Cleanroom or isolator integrable \u2013 with optional 21 CFR Part 11 compatible software<\/li>\n<li>Decreases cycle development time and conserves valuable API<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading has-text-color\">Accessories &amp; Consumables<\/h3>\n<p>Accessories: Sample Extractor, MVP probes, Leveling Feet, 21 CFR Part 11<\/p>\n<p>Consumable Parts Kit and Critical Components Spare Parts.<\/p>\n<p>Optional\u00a0<a href=\"https:\/\/scientificproducts.com\/products\/controlyo-nucleation-technology\/\" target=\"_blank\" rel=\"noopener\">ControLyo<\/a><a href=\"https:\/\/www.scientificproducts.com\/products\/controlyo\">\u00ae<\/a>,\u00a0<a href=\"https:\/\/scientificproducts.com\/products\/lyoflux-200-tdlas-sensors\/\" target=\"_blank\" rel=\"noopener\">LyoFlux* TDLAS<\/a>\u00a0and\u00a0<a href=\"https:\/\/scientificproducts.com\/products\/tempris-wireless-sensors\/\" target=\"_blank\" rel=\"noopener\">Tempris* Wireless Probes<\/a><\/p>\n<h4 class=\"wp-block-heading has-text-color\">Application Examples<\/h4>\n<ul>\n<li>Formulation Development &amp; Stability Studies<\/li>\n<li>Cycle Optimization &amp; Scale-up<\/li>\n<li>Lyophilization of Product with Organic Solvents in Addition to Water<\/li>\n<li>Laboratory Research &amp; Development Freeze-Drying<\/li>\n<li>Diagnostic Kits<\/li>\n<li>96-Well Plates<\/li>\n<li>Serum Bottles &amp; Vials<\/li>\n<\/ul>\n<div>\n<p>for <b><a href=\"https:\/\/scientificproducts.com\/products\/sp-hull-lyostar-4-0-rd-process-development-freeze-dryer\/\" target=\"_blank\" rel=\"noopener\">MORE INFORMATION<\/a> <\/b>or <a href=\"http:\/\/iss-lab.com\/?page_id=78\" target=\"_blank\" rel=\"noopener\"><strong>CONTACT US<\/strong><\/a><\/p>\n<p><strong>PRODUCT SPECIFICATION<\/strong><\/p>\n<\/div>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/SP-Hull-LyoStar-4.0-Spec-Sheet.pdf\" target=\"_blank\" rel=\"noopener\"><strong>LyoStar\u00ae 4.0 | Research and Development Tray Freeze Dryer<\/strong><\/a><\/li>\n<\/ul>\n<ul>\n<li class=\"_3vbdr sc-frDJqD fDQgcn\"><a href=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_4.0_freeze_dryer-720p.mp4\" target=\"_blank\" rel=\"noopener\"><strong><span class=\"-KXLs\">SP Hull LyoStar 4.0 Freeze Dryer &#8211; Video<\/span><\/strong><\/a><\/li>\n<\/ul>\n<div style=\"width: 750px;\" class=\"wp-video\"><!--[if lt IE 9]><script>document.createElement('video');<\/script><![endif]-->\n<video class=\"wp-video-shortcode\" id=\"video-539-1\" width=\"750\" height=\"422\" poster=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/ControLyo.png\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_4.0_freeze_dryer-720p.mp4?_=1\" \/><a href=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_4.0_freeze_dryer-720p.mp4\">https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_4.0_freeze_dryer-720p.mp4<\/a><\/video><\/div>\n<h1><\/h1>\n<p><strong>Related Products<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/products\/sp-hull-lyostar-bi-i-l-filler\/\" target=\"_blank\" rel=\"noopener\"><strong>Hull LyoStar\u00ae BI I\/L Filler<\/strong><\/a><\/li>\n<li><strong><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/SP-Hull-LyoStar-BI-I-L-Filler-Spec-Sheet.pdf\" target=\"_blank\" rel=\"noopener\">Hull LyoStar\u00ae BI I\/L Filler &#8211; Spec. Sheet<\/a><\/strong><\/li>\n<li><a href=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_bi_i_l_filler-540p.mp4\" target=\"_blank\" rel=\"noopener\"><strong>Hull LyoStar\u00ae BI I\/L Filler &#8211; Video<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"width: 750px;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-539-2\" width=\"750\" height=\"422\" poster=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/SP-HULL-LYOSTAR-BI-I-L-FILLER-2022_modified.png\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_bi_i_l_filler-540p.mp4?_=2\" \/><a href=\"https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_bi_i_l_filler-540p.mp4\">https:\/\/iss-lab.com\/wp-content\/uploads\/2013\/11\/sp_hull_lyostar_bi_i_l_filler-540p.mp4<\/a><\/video><\/div>\n<h1><\/h1>\n<p><strong>PRODUCT BULLETIN<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/LyoStar-4.0_SP-Hull-Product-Bulletin.pdf\" target=\"_blank\" rel=\"noopener\"><strong>SP Hull LyoStar\u00ae 4.0 Freeze Dryer for Rapid Lyophilization Cycle Development and Scale-up |\u00a0<\/strong><\/a><br \/>\n<a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/LyoStar-4.0_SP-Hull-Product-Bulletin.pdf\" target=\"_blank\" rel=\"noopener\">Incorporating the Line-of-Sight\u2122 Approach<\/a><\/li>\n<\/ul>\n<p><strong>WHITE PAPER<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/White-Paper-Technologies-PAT-Tools-To-Overcome-Lyo-Challenges.pdf\" target=\"_blank\" rel=\"noopener\"><strong>Utilization Of Technologies And Process Analytical Tools To Overcome Lyophilization Challenges During Development, Scale\u2011Up And Manufacturing Of Biologic Products<\/strong><\/a><\/li>\n<\/ul>\n<p><strong>TECH NOTE<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/scientificproducts.com\/wp-content\/uploads\/sites\/58\/2023\/08\/SP-Tech-Note-Basic-Principles-of-Freeze-Drying-6.pdf\" target=\"_blank\" rel=\"noopener\"><strong>Basic Principles of Freeze-Drying<\/strong><\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Ideal for rapid lyophilization cycle development, optimization and scale-up, the Hull LyoStar\u00ae 4.0 R&amp;D and Process Development Freeze Dryer incorporates the very latest innovations in freeze-drying technology. Ensure precise process control and reliability, and protect your valuable product, with us! Unparalleled uniformity \u2013 superior shelf temperature mapping and rapid shelf freezing Ecologically sound \u2013 reduced [&hellip;]<\/p>\n","protected":false},"author":45,"featured_media":0,"parent":200,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"_links":{"self":[{"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/pages\/539"}],"collection":[{"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/users\/45"}],"replies":[{"embeddable":true,"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/comments?post=539"}],"version-history":[{"count":8,"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/pages\/539\/revisions"}],"predecessor-version":[{"id":3076,"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/pages\/539\/revisions\/3076"}],"up":[{"embeddable":true,"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/pages\/200"}],"wp:attachment":[{"href":"https:\/\/iss-lab.com\/index.php\/wp-json\/wp\/v2\/media?parent=539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}